Ana buƙatar wasu hanyoyin magance matsalar maganin rigakafi saboda haramcin amfani da waɗannan magunguna a matsayin masu haɓaka ci gaba a samar da dabbobin abinci. Tributyrin yana taka rawa wajen inganta ci gaban alade, duk da cewa yana da tasiri daban-daban.

Zuwa yanzu, ba a san komai game da tasirinsa ga tsarin ƙwayoyin cuta na hanji ba. A cikin wannan binciken, mun binciki canje-canjen ƙwayoyin cuta na hanji na 'yan aladu da suka karɓi magani, lokacin da aka yaye su, an ƙara kashi 0.2% na tributyrin a cikin abincinsu na asali.

Ƙungiyar Tributyrin tana da ƙarfin haɓaka metabolism na makamashi da kuma raguwar damar metabolism na carbohydrate. A ƙarshe, sakamakonmu ya nuna cewa tributyrin na iya haɓaka canje-canje ga al'ummomin ƙwayoyin cuta na hanji, wanda zai iya taimakawa wajen inganta aikin dabbobi bayan an yaye su.

Tasirin Tributyrin akan Canje-canjen ƙwayoyin cuta na hanji da suka shafi Ayyukan Yaye Alade

Sigogin Samfura

Tributyrin (wanda kuma ake kira Glyceryl tributyrate; Glycerol tributyrate; Glyceryl tributyrate; propane-1,2,3-triyl tributanoate) wani nau'in ester ne na gajeren sarkar kitse mai kitse.

CAS RN: 60-01-5

Lambar EINECS: 200-451-5

Ma'aunin Halitta: C15H26O6

FW: 302.36

Bayyana: Ruwan mai ne fari zuwa rawaya, mai ɗan ƙamshi mai ɗan kitse.

Narkewa: Yana narkewa a cikin ethanol, chloroform da ether, da kyar yake narkewa a cikin ruwa (0.010%).

Rayuwar Shiryayye: Watanni 24

Kunshin: 25KG/ Jaka

Ajiya: An rufe a wuraren busassu da wuraren da iska ke shiga

Tributyrinwani sinadari ne mai suna triglyceride wanda ke ɗauke da ƙwayoyin butyrate guda uku da aka haɗa su zuwa glycerol, yana ƙara yawan butyrate bayan an yi amfani da hydrolyzation ta hanyar pancreas lipases.

Halaye na Tributyrin
Sabuwar ƙarni na butyrate-glycerol ester na butyric acid.
Ciki mai kauri 100%.
Yana isar da butyric acid zuwa ƙaramin hanji, ba sai an shafa shi ba.
A dabi'ance ana samunsa a cikin madara da zuma.

Kwatanta Tsakanin Tributyrin da Gishirin Butyrate

Rabin rayuwar butyric acid minti 6 ne. Butyrate yana da wuya ya isa ga sauran kyallen takarda da gabobin da ke wajen hanji da aka ba shi ta hanyar butyric acid ko butyrate. Duk da haka, rabin rayuwar tributyrin minti 40 ne, kuma yawan sinadarin butyrate a cikin jini za a iya kiyaye shi sama da 0.1mM na tsawon awanni 0.5-4 ta hanyar baki.

Tsarin aiki & Siffofi

Mai Samar da Makamashi

Kamar yadda aka sani, butyric acid wani sinadari ne mai ɗan gajeren sarka wanda shine babban tushen kuzarin ƙwayoyin epithelial na hanji. Fiye da kashi 70% na kuzarin da ake buƙata don haɓakar ƙwayoyin epithelial na hanji ana samar da shi ne ta hanyar butyric acid. Duk da haka, tributyrin yana samar da mafi girman ƙimar butyric acid mai sakin hanji idan aka kwatanta da sauran samfuran butyrate.

Kariyar Gut

►Tributyrin yana haɓaka yaduwa da bambance-bambancen ƙwayoyin epithelial na mucosa na hanji, yana gyara mucosa da ya lalace, kuma yana faɗaɗa yankin saman don shan abubuwan gina jiki.

►Tributyrin yana haɓaka bayyanar sunadaran haɗin gwiwa masu ƙarfi a cikin hanji, yana kula da haɗuwa mai ƙarfi tsakanin ƙwayoyin halitta, yana hana ƙwayoyin cuta kamar ƙwayoyin cuta da guba shiga jiki, kuma yana kula da aikin shinge na hanji.

►Tributyrin yana haɓaka fitar da mucin (Muc) kuma yana ƙarfafa aikin shingen sinadarai na hanji.

Inganta Yawan Rayuwa

Tributyrin na iya haɓaka haɗakar haemoglobin, inganta ikon ɗaukar iskar oxygen, ƙarfafa tsarin tallafawa rayuwa ta ciki, kuma yana iya inganta aikin mitochondria da haɓaka haɗakar ATP, sinadari mai kuzari wanda ke motsa ayyukan rayuwa. Don inganta yawan rayuwa ko dabbobi.

Maganin Kumburi da Kwayoyin cuta

►Ta hanyar hana ayyukan NF-Kb, TNF-α da TLR, Tributyrin zai iya rage lalacewar kumburi.

►Tributyrin yana haɓaka bayyanar peptides na kariya daga ƙwayoyin cuta, waɗanda zasu iya tsayayya da ƙwayoyin cuta da ƙwayoyin cuta gabaɗaya.